Greetings from Parents

Faster than the wind...
Stronger than the rock,
You've always been there....
Whenever I needed you!
Thanks for being a friend
Who is always close to my heels

Dear all,

We are fine here. I am sending you an e-Card just to greet you.

With love, Amma - Naana

Ugadi Greetings

Fresh Hopes and Renewed Vigour
mark the celebrations of a New Year.

And with the onset of Spring,
one can enjoy the chirping of birds,
the early morning chills
and the blooming of colourful flowers.

Especially the fragrance of the
blossoming neem flowers
in the air announces the arrival of
the New Year, Ugadi

WITH LOVE, AMMA - NAANA

Also here is a poem written in Telugu by Mr.Gopal Reddy, a friend of mine :Poem on Ugadi

In only one of these lies happiness.

There is work that is work and there is play that is play; there is play that is work and work that is play. And in only one of these lies happiness.

With Love, Amma-Naana

Aparna's Research on Anti Hypertensive Drugs

Dear Amma, Nana and Dear All:

Here we are fine hope the same from you all.

Our research work on anti hypertensive drugs is published recently in the following journal and conference reports. These are our joint publications with Pfizer.

Have a nice day.

With love, Akkaiah.
March 23, 2006


Journal Article:

Ketopiperazine-based renin inhibitors: Optimization of the "C" ring. Holsworth Daniel D; Cai Cuiman; Cheng Xue-Min; Cody Wayne L; Downing Dennis M; Erasga Noe; Lee Chitase; Powell Noel A; Edmunds Jeremy J; Stier Michael; Jalaie Mehran; Zhang Erli; McConnell Pat; Ryan Michael J; Bryant John; Li Tingsheng; Kasani Aparna; Hall Eric; Subedi Rajendra; Rahim Mohammad; Maiti Samarendra Pfizer Global Research and Development, Michigan Laboratories, Department of Chemistry, Ann Arbor, MI 48105, USA Bioorganic & medicinal chemistry letters (2006), 16(9), 2500-4.


Conference Reports:

Discovery of novel orally bioavailable renin inhibitors by structure based drug design. Edmunds, Jeremy J.; Belliotti, Thomas; Bryant, John; Cai, Cuiman; Cheng, Xue Min; Ciske, Fred L.; Cody, Wayne L.; Collard, Wendy; Downing, Dennis M.; Erasga, Noe; Ferreira, Suzie; Hall, Eric; Holsworth, Daniel D.; Jalaie, Mehran; Kasani, Aparna; Kaufman, Michael; Lee, Chitase; Li, Tingsheng; Maiti, Samarendra; McConnell, Patrick; Mennen, Ken; Ostroski, Robert; Powell, Noel A.; Quin, John; Rahim, Mohammad; Ryan, Michael; Stier, Michael A.; Subedi, Rajandra; Van Huis, Chad; Zhang, Erli. Michigan Laboratories, Pfizer Global Research & Development, Ann Arbor, MI, USA. Abstracts of Papers, 231st ACS National Meeting, Atlanta, GA, United States, March 26-30, 2006 (2006), Publisher: American Chemical Society, Washington, D. C

Ketopiperazine-based renin inhibitors: Optimization of the "C" ring: Incorporation of indole rings. Cai, Cuiman; Bryant, John; Cheng, Xue Min; Cody, Wayne L.; Collard, Wendy; Downing, Dennis M.; Erasga, Noe; Ferreira, Suzie; Hall, Eric; Holsworth, Daniel D.; Jalaie, Mehran; Kasani, Aparna Lee, Chitase; Li, Tingsheng; Maiti, Samarendra; McConnell, Patrick; Powell, Noel A.; Rahim, Mohammad; Ryan, Michael; Stier, Michael A.; Subedi, Rajandra; Zhang, Erli; Edmunds, Jeremy J. Michigan Laboratories, Pfizer Global Research & Development, Ann Arbor, MI, USA. Abstracts of Papers, 231st ACS National Meeting, Atlanta, GA, United States, March 26-30, 2006 (2006), Publisher: American Chemical Society, Washington, D. C

Discovery of 6-ethyl-2,4-diaminopyrimidine-based small molecule renin inhibitors. Holsworth, Daniel D.; Belliotti, Thomas; Bryant, John; Cai, Cuiman; Cody, Wayne L.; Downing, Dennis M.; Jalaie, Mehran; Kasani, Aparna; Li, Tingsheng; Maiti, Samarendra; McConnell, Patrick; Powell, Noel A.; Ryan, Michael; Subedi, Rajandra; Zhang, Erli; Edmunds, Jeremy J. Michigan Laboratories, Pfizer Global Research & Development, Ann Arbor, MI, USA. Abstracts of Papers, 231st ACS National Meeting, Atlanta, GA, United States, March 26-30, 2006 (2006), Publisher: American Chemical Society, Washington, D. C

Courage does not always roar.

Dear Children,

Thanks for your emails and phone calls.

- Courage does not always roar. Sometimes, it is the quiet voice at the end of the day saying, "I will try again tomorrow".

- To think bad thoughts is really the easiest thing in the world. If you leave your mind to itself it will spiral down into ever increasing unhappiness. To think good thoughts, however, requires effort. This is one of the things that discipline - training - is about.

With Love, Amma-Nana

Values - By Gandhi

Keep your thoughts positive
because your thoughts become your words.

Keep your words positive
because your words become your behaviors.

Keep your behaviors positive
because your behaviors become your habits.

Keep your habits positive
because your habits become your values.

Keep your values positive
because your values become your destiny.

With Love, Amma-Nana

Manasu - Manishi - Prakruthi

Happiness is not what happens to us, but how we choose to respond to what happens.

Dear Children,

We make decisions with our head, And we make commitments with our heart. The choices we made yesterday have impacted our success today, while the choices we will make today will impact our success tomorrow. Happiness is not what happens to us, but how we choose to respond to what happens.

With Best Wishes, AMMA - NAANA

Excellence is a habit

Dear Children, GOOD AFTERNOON!

The secret of our success is found in our daily agenda!

There are 86,400 seconds in a day. It's up to us to decide what to do with them. Let us make each day our masterpiece. Excellence is not an act, but a habit.

With love, Amma-Naana

How are you ... From a Daughter

Dear sir,

how are u, how is ur health now,

I have given a reply to your son, Ajay today, because in our hospital net was not working that's why its delayed, sorry for that! . Sir i like u very much, because of your talking style and behavior.

Give me reply as soon as possilbe.

With regards
Urs daughter
lakshmi

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Nice to receive your mail, dear KONDA .

We have already two sweet Konda`s. I call them Chinnakonda and Peddakonda. Now you are added to my account. Yes! I too like you very much. I like your straightforwardness mostly. Yes! let us keep in touch with each other and let us exchange our news and views.

I shall close my mail wishing you all the best!

With love, Naana

Embracing This Present Moment

1. It is only when we truly know and understand that we have a limited time on earth—and that we have no way of knowing when our time is up—that we will begin to live each day to the fullest, as if it was the only one we had.
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2. This time, like all times, is a very good one if we but know what to do with it.
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3. By taking good care of the present moment, we take good care of the future.
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4. We can only be happy now, and there will never be a time when it is not now.
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5. I like to remind my friends frequently how short life is. This is the important message of death: not a day to waste, not a day to quarrel, not a day to brood upon yourself. This is not losing the joy of life; this is gaining the joy of life.
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6. Don’t take yourself and your life so seriously, forgetting that life is meant to be a great adventure to be lived fully. When you become too serious, life loses its luster and you have a hard time being happy.
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7. Climb the mountains and get their good tidings. Nature's peace will flow into you as sunshine flows into trees. The winds will blow their own freshness into you, and the storms their energy, while cares will drop off like autumn leaves.
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8. Look at everything as though you were seeing it for the first time or the last time. Then your time on earth will be filled with glory.
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9. Don’t say you don’t have enough time. You have exactly the same number of hours per day that were given to Helen Keller, Pasteur, Michelangelo, Mother Teresa, Leonardo da Vinci, Thomas Jefferson, and Albert Einstein.
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10. Laughter is the lubricant and elixir of life. Being able to laugh at yourself and the everyday incongruities of your daily situation is the best way to quell stress. Lighten up and enjoy life!
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11. The secret of forgiveness is not to procrastinate, but to free yourself immediately of stress by totally forgiving this instant.
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12. Birds sing after a storm, why shouldn’t we?
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13. The secret of health for both mind and body is not to mourn for the past, not to worry about the future, not to anticipate troubles, but to live the present moment wisely and earnestly.


With Love, Amma-Nana

My Mother Taught Me...

1. My Mother taught me about ANTICIPATION...
"Just wait until your father gets home."

2. My Mother taught me about RECEIVING....
"You are going to get it when we get home!"

3. My Mother taught me to MEET A CHALLENGE...
"What were you thinking? Answer me when I talk to you ... Don't talk back to me!"

4. My Mother taught me LOGIC...
"If you fall out of that swing and break your neck, your not going to the store with me."

5. My Mother taught me MEDICAL SCIENCE...
"If you don't stop crossing your eyes, they are going to freeze that way."

6. My Mother taught me to THINK AHEAD...
"If you don't pass your spelling test, you'll never get a good job."

7. My Mother taught me ESP...
"Put your sweater on; don't you think I know when you're cold?"

8. My Mother taught me HUMOR...
"When that lawn mower cuts off your toes, don't come running to me."

9. My Mother taught me how to BECOME AN ADULT...
"If you don't eat your vegetables, you'll never grow up."

10. My Mother taught me about SEX....
"How do you think you got here?"

11. My Mother taught me about GENETICS...
"You're just like your father."

12. My Mother taught me about my ROOTS...
"Do you think you were born in a barn?"

13. My Mother taught me about WISDOM OF AGE...
"When you get to be my age, you will understand."

14. And my all time favorite... JUSTICE...
"One day you'll have kids, and I hope they turn out
just like you....then you'll see what it's like"

~ With Love, Amma-Nana

For you to think..

The ultimate measure of a man is not where he stands in moments of comfort and convenience, but where he stands at times of challenge and controversy

A parent is not a person to lean on, but a person to make leaning unnecessary!

With Love, Amma-Nana

We are doing well

Dear all, GOOD MORNING.

I am fine here. I am writing this email from Apollo Hospitals, Hyderabad. Today doctor is expected to be here after noon only. Dr. DVSLN Sharma, another urologist is presently available here. But I decided to see Dr. Rajagopal only. So I am waiting for him. I am quite comfortable. In between I am taking Coconut water as well.

Ms. R K Lakshmi, who is the secretary of Dr. Rajagopal is friendly to me. Her date of birth is 1977. She has one year old daughter.

With love, Naana
March 7, 2006.

Some proverbs for us to read and think them over.

-A coward dies a thousand times before his death. The valiant never tastes of death but once.
-All problems become smaller if you don’t dodge them, but confront them. Touch a thistle timidly, and it pricks you; grasp it boldly, and its spines crumble.
-Being deeply loved by someone gives you strength while loving someone deeply gives you courage.
-Courage easily finds its own eloquence.
-Courage is like a muscle; it is strengthened by use.
-Courage is like love, it must have hope for nourishment.
-Courage is not the lack of fear. It is acting in spite of it.
-Courage is rightly esteemed the first of human qualities because it is the quality which guarantees all others.
-Every great work, every big accomplishment, has been brought into manifestation through holding to the vision, and often just before the big achievement, comes apparent failure and discouragement.
-Everyone has talent. What is rare is the courage to follow that talent to dark place where it leads.
-Few things are more attractive than courage, cheerfulness and optimism. But they take on an extra dimension when you realize that they are not a lucky assembly of character traits, but the result of an act of will—a deliberate attempt to tackle an unkind destiny with strength of purpose and good humor.
-Flatter me, and I may not believe you. Criticize me, and I may not like you. Ignore me, and I may not forgive you. Encourage me, and I will not forget you.
-Great occasions do not make heroes or cowards; they simply unveil them to the eyes. Silently and imperceptibly, as we wake or sleep, we grow strong or we grow weak, and at last some crisis shows us what we have become.
-If we could be heroes, if just for one day.
-If you're careful enough, nothing bad or good will ever happen to you.
-Life is a compromise of what your ego wants to do, what experience tells you to do, and what nerves let you do.
-One man with courage makes a majority.
-The greatest test of courage on the earth is to bear defeat without losing heart.

With Love, Amma-Nana

Congratulations To Sushma

Dear Sushma:

We are very happy to hear the good news. CONGRATULATIONS !. I am sure it will be an exiting new job and you will do well. Our warm wishes are with you. Take care.

Link for your Info: www.yicrlaw.com

With love, Somaiah Mamaiah

Keep Our Ideals

* Nobody grows old merely by living a number of years. We grow old by deserting our ideals.

* Waste your money and you're only out of money, but waste your time and you've lost part of your life.

With love, Amma-Naana

We wish you all a Happy " Maha Shivaratree"

Dear all,

Happy to know the details of all our dear people. We Wish You all a Happy " Maha Shivaratree".

With love,
Amma - Naana